Endocrine Abstracts

Androgens are one of the most important agents influencing folliculogenesis. They can modulate follicular function by interactions with various factors and promote granulosa cells differentiation. On the other hand, androgens can antagonize follicular development by inducing apoptosis in granulosa cells. Therefore, androgens can promote follicular atresia. The purpose of the present study was to test the hypothesis that androgen receptor antagonists (2-hydroxyflutamide (2-Hf) ...